MK-677
t½ 5 hoursA non-peptide, orally active growth hormone secretagogue that mimics ghrelin and provides sustained GH and IGF-1 elevation.
Dosing Ranges
Low (10 mg)
Starting dose
Standard (15 mg)
Standard dose
High (25 mg)
Aggressive dose
Doses are in mcg per kg of body weight. Use the Dosage Calculator to get your exact dose.
Protocol Details
Frequency
1x daily (oral)
Cycle Length
8–12 weeks, or ongoing with monitoring
Administration
Oral
Research Notes
- 1Orally active — no injection needed. Typically sold as capsules or liquid.
- 2Pharmacokinetic half-life is 4-6 hours. IGF-1 elevation persists ~24 hours.
- 3Can increase appetite, water retention, and fasting blood glucose.
- 4Monitor fasting glucose and HbA1c with long-term use.
- 5Not technically a peptide — it is a non-peptide GHS mimetic.
Common Vial Sizes
Calculate your dose
Enter your body weight to get your exact dose in mcg for MK-677.
Open Dosage CalculatorMore tools
Where to source peptides
Research Use OnlyApollo Peptides
High-purity peptides, COA on every batch
Peptide Sciences
US-based, 98%+ purity, fast shipping
Limitless Life Nootropics
Wide catalog, quantity discounts
For research use only. PepStack may earn a commission on purchases made through these links — at no extra cost to you.
For informational and research tracking purposes only. Not medical advice. Always consult a qualified healthcare professional before starting any peptide protocol.
Sources & References
User Reviews
PepStack is for research and educational purposes only. This is not medical advice. Always consult a qualified healthcare provider before using any peptides. Dosing data is sourced from published research and community protocols — verify with your provider.
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