Sermorelin

10 minutes
GRF 1-29Geref

A growth hormone-releasing hormone (GHRH) analog consisting of the first 29 amino acids of endogenous GHRH. Stimulates pituitary GH release.

Dosing Ranges

Conservative

Starting dose

2 mcg/kg

Standard

Standard dose

3.5 mcg/kg

Aggressive

Aggressive dose

5 mcg/kg

Doses are in mcg per kg of body weight. Use the Dosage Calculator to get your exact dose.

Protocol Details

Frequency

1x daily before bed

Cycle Length

3–6 months

Administration

Subcutaneous injection

Research Notes

  • 1FDA-approved (as Geref) for diagnostic use; previously approved for GH deficiency in children.
  • 2Very short half-life — best administered before bed to amplify the natural nocturnal GH pulse.
  • 3Often combined with a GHRP (e.g., GHRP-2, GHRP-6, Ipamorelin) for synergistic GH release.
  • 4Considered one of the mildest GHRH analogs with a long safety track record.

Common Vial Sizes

2 mg5 mg15 mg

Calculate your dose

Enter your body weight to get your exact dose in mcg for Sermorelin.

Open Dosage Calculator

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For informational and research tracking purposes only. Not medical advice. Always consult a qualified healthcare professional before starting any peptide protocol.

Sources & References

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PepStack is for research and educational purposes only. This is not medical advice. Always consult a qualified healthcare provider before using any peptides. Dosing data is sourced from published research and community protocols — verify with your provider.

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