Back to Blog
BPC-157TB-500BlendsCalculator

Peptide Blend Calculator: How to Dose BPC-157/TB-500 Blends

Learn what peptide blends are, how to calculate individual peptide doses from a blend vial, common blend ratios, and practical tips for accurate dosing.

·8 min read

What Is a Peptide Blend?

A peptide blend is a single vial that contains two or more peptides combined together in lyophilized form. Instead of purchasing separate vials of BPC-157 and TB-500 and reconstituting them individually, a blend vial contains both peptides in a fixed ratio.

The most common blend is BPC-157 + TB-500, but other combinations exist including Ipamorelin + CJC-1295 blends and multi-peptide recovery blends.

Why Blends Exist

Blends offer several practical advantages:

  • Fewer vials to manage and store
  • Single reconstitution instead of multiple
  • One injection delivers both peptides
  • Simplified protocol — less room for dosing errors across multiple vials

The trade-off is that you lose the ability to independently adjust the dose of each individual peptide.

Understanding Blend Labels

Blend vials are labeled with the total amount of each peptide. For example:

"BPC-157 5mg / TB-500 5mg Blend"

This means the vial contains 5 mg of BPC-157 AND 5 mg of TB-500 — a total of 10 mg of combined peptide.

Other common label formats:

  • BPC/TB 5/5 → 5 mg BPC-157 + 5 mg TB-500
  • BPC/TB 10/10 → 10 mg BPC-157 + 10 mg TB-500
  • BPC-157 2.5mg / TB-500 5mg → unequal amounts (different ratio)

Always read the label carefully. The ratio determines how much of each peptide you get per unit of volume.

How to Calculate Individual Doses from a Blend

Step 1: Determine the Concentration of Each Peptide

After reconstituting, each peptide has its own concentration:

Concentration of Peptide A = Amount of Peptide A (mcg) / Total water added (mL)

Step 2: Calculate Injection Volume for Your Target Dose

Decide which peptide's dose you want to target, then calculate the volume:

Volume (mL) = Target dose (mcg) / Concentration (mcg/mL)

Step 3: Calculate the Corresponding Dose of the Other Peptide

Once you know the volume, multiply by the other peptide's concentration to see how much of it you are getting.

Worked Example: BPC-157 5mg / TB-500 5mg Blend

Reconstitution

Add 2 mL of bacteriostatic water to the vial.

Concentrations

  • BPC-157: 5,000 mcg / 2 mL = 2,500 mcg/mL
  • TB-500: 5,000 mcg / 2 mL = 2,500 mcg/mL

Dosing for 500 mcg BPC-157

  • Volume: 500 / 2,500 = 0.20 mL (20 units)
  • TB-500 in that volume: 0.20 mL x 2,500 = 500 mcg TB-500

In a 1:1 blend, targeting 500 mcg of BPC-157 automatically gives you 500 mcg of TB-500.

Dosing for 250 mcg BPC-157

  • Volume: 250 / 2,500 = 0.10 mL (10 units)
  • TB-500 in that volume: 0.10 mL x 2,500 = 250 mcg TB-500

Common Blend Ratios

BlendRatioCommon Vial SizesNotes
BPC-157 / TB-5001:15/5 mg, 10/10 mgMost common healing blend
BPC-157 / TB-5001:25/10 mgHigher TB-500 for systemic inflammation
Ipamorelin / CJC-12951:13/3 mg, 5/5 mgGH secretagogue blend
BPC-157 / GHK-Cu1:15/5 mgHealing + skin/tissue repair

The Key Limitation of Blends

With a blend, the ratio is fixed. If you want 500 mcg of BPC-157 but only 250 mcg of TB-500, you cannot achieve this from a 1:1 blend — you would need separate vials.

This matters when:

  • You want to titrate one peptide independently
  • One peptide causes side effects and you want to reduce just that one
  • The optimal dose ratio for your goals differs from the blend ratio

For full flexibility, use separate vials and the Reconstitution Calculator to calculate each peptide independently.

Tips for Dosing Blends Accurately

  • Always reconstitute with a measured amount of BAC water — use a syringe to add water, not a dropper. Precision matters.
  • Record the water volume on the vial label with the date of reconstitution.
  • Use U-100 insulin syringes for consistent, accurate measurements.
  • Calculate both peptide doses before injecting — make sure the secondary peptide dose is within an acceptable range.
  • Use the Syringe Calculator to verify your injection volume corresponds to the correct syringe markings.

Sample Protocol: BPC-157/TB-500 Blend for Recovery

Using a 10/10 mg blend (10 mg BPC-157 + 10 mg TB-500), reconstituted with 4 mL BAC water:

  • BPC-157 concentration: 2,500 mcg/mL
  • TB-500 concentration: 2,500 mcg/mL

Daily dose: 0.20 mL (500 mcg BPC-157 + 500 mcg TB-500)

Doses per vial: 4 mL / 0.20 mL = 20 doses (20 days at once daily)

Protocol

  • Weeks 1–4 (loading): 500 mcg each, once daily, subcutaneously near injury site
  • Weeks 5–8 (maintenance): 250 mcg each, once daily (0.10 mL)

Disclaimer

This guide is for informational and educational purposes only and does not constitute medical advice. BPC-157 and TB-500 are research peptides not approved by the FDA for human use. Consult a qualified healthcare professional before starting any peptide protocol.

Trusted Suppliers

For research use only · PepStack may earn a commission on purchases

Disclaimer: This article is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any peptide protocol.